Influence of obesity on the risk of esophageal disorders

  title={Influence of obesity on the risk of esophageal disorders},
  author={J. Lagergren},
  journal={Nature Reviews Gastroenterology &Hepatology},
  • J. Lagergren
  • Published 2011
  • Medicine
  • Nature Reviews Gastroenterology &Hepatology
  • Obesity is associated with an increased risk of esophageal disorders, including esophageal adenocarcinoma, Barrett esophagus and GERD. For reasons yet unknown, the association between obesity and esophageal adenocarcinoma seems to be stronger than that for other types of obesity-related cancers. Predominantly abdominal or intra-abdominal adiposity (representing visceral fat and other fat within the abdominal cavity), which is more frequently observed in men than in women, is more strongly… CONTINUE READING
    137 Citations

    Figures, Tables, and Topics from this paper.

    The association between obesity factor and esophageal caner.
    • 27
    Pathophysiological mechanisms linking obesity and esophageal adenocarcinoma.
    • 31
    Obesity and esophageal cancer: GERD, Barrett´s esophagus, and molecular carcinogenic pathways
    • 1
    The Epidemiology of Esophageal Adenocarcinoma.
    • 52
    • PDF
    Gastrointestinal Complications of Obesity.
    • 68
    Epidemiology of Barrett's Esophagus and Esophageal Adenocarcinoma.
    • 90
    • PDF
    Central adiposity is associated with increased risk of esophageal inflammation, metaplasia, and adenocarcinoma: a systematic review and meta-analysis.
    • S. Singh, Anamay N. Sharma, +4 authors P. Iyer
    • Medicine
    • Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
    • 2013
    • 221


    Abdominal Obesity and the Risk of Esophageal and Gastric Cardia Carcinomas
    • 190
    • PDF
    Adenocarcinoma of the esophagus: role of obesity and diet.
    • 392
    Epidemiology of adenocarcinoma of the esophagus, gastric cardia, and upper gastric third.
    • Manuel Vial, L. Grande, M. Pera
    • Medicine
    • Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer
    • 2010
    • 87
    Lack of differential pattern in central adiposity and metabolic syndrome in Barrett's esophagus and gastroesophageal reflux disease.
    • 26
    Obesity, alcohol, and tobacco as risk factors for cancers of the esophagus and gastric cardia: adenocarcinoma versus squamous cell carcinoma.
    • T. Vaughan, Susan. Davis, A. Kristal, D. Thomas
    • Medicine
    • Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
    • 1995
    • 527
    • PDF
    Abdominal Obesity and the Risk of Barrett's Esophagus
    • 200