Influence of non-steroidal anti-inflammatory drugs on renal function and 24h ambulatory blood pressure-reducing effects of enalapril and nifedipine gastrointestinal therapeutic system in hypertensive patients.

@article{Polnia1995InfluenceON,
  title={Influence of non-steroidal anti-inflammatory drugs on renal function and 24h ambulatory blood pressure-reducing effects of enalapril and nifedipine gastrointestinal therapeutic system in hypertensive patients.},
  author={Jorge Pol{\'o}nia and I Boaventura and Guilherme M Gama and Izabel Coelho Gomes Cam{\~o}es and Fernando Bernardo and Paulo Andrade and Jos{\'e} Pedro L Nunes and Filipe Brand{\~a}o and M{\'a}rio Cerqueira-Gomes},
  journal={Journal of hypertension},
  year={1995},
  volume={13 8},
  pages={925-31}
}
OBJECTIVE To evaluate the influence of non-steroidal anti-inflammatory drugs (NSAIDs; aspirin and indomethacin) on the renal and antihypertensive effects of enalapril and nifedipine gastrointestinal therapeutic system (GITS) in patients with essential hypertension. DESIGN AND METHODS In a crossover study, 18 patients on an unrestricted-salt diet were randomly assigned to receive either enalapril (20-40 mg/day) or nifedipine-GITS (30-60 mg/day) for 4-8 weeks, followed by aspirin (100 mg/day… CONTINUE READING

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