Influence of neutralizing antibodies to adalimumab and infliximab on the treatment of psoriasis.

@article{Bito2014InfluenceON,
  title={Influence of neutralizing antibodies to adalimumab and infliximab on the treatment of psoriasis.},
  author={Toshinori Bito and Ryutaro Nishikawa and M. Hatakeyama and Ayuko Kikusawa and Haruhisa Kanki and Hideo Nagai and Yasuko Sarayama and Tokunori Ikeda and Hitomi Yoshizaki and Hiroshi Seto and Ayumi Adachi and T. Horikawa and Masaki Oka and Chikako Nishigori},
  journal={The British journal of dermatology},
  year={2014},
  volume={170 4},
  pages={
          922-9
        }
}
  • Toshinori Bito, Ryutaro Nishikawa, +11 authors Chikako Nishigori
  • Published in
    The British journal of…
    2014
  • Medicine
  • BACKGROUND Current treatment with biologics has produced dramatic therapeutic effects in patients with psoriasis, although these agents occasionally decrease in efficacy. One of the main factors responsible for this attenuation is attributed to the development of antidrug antibodies (ADAs). OBJECTIVES To analyse the relationship between serum drug concentrations, the presence of ADAs and treatment efficacy of adalimumab and infliximab, and to determine the optimal use of these biologics… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Figures, Tables, and Topics from this paper.

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 24 CITATIONS

    Therapeutic drug monitoring of biologics in psoriasis

    VIEW 1 EXCERPT
    CITES BACKGROUND

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 19 REFERENCES

    single-centre, cohort study

    • H Takahashi, H Tsuji, Y Hashimoto
    • Br J Dermatol
    • 2013

    Therapeutic drug monitoring of tumor necrosis factor antagonists in inflammatory bowel disease.