Influence of nephrectomy on tumor necrosis factor clearance in a murine model.

@article{Bemelmans1993InfluenceON,
  title={Influence of nephrectomy on tumor necrosis factor clearance in a murine model.},
  author={Marc H. A. Bemelmans and Dirk. J. Gouma and Wim A. Buurman},
  journal={Journal of immunology},
  year={1993},
  volume={150 5},
  pages={2007-17}
}
TNF, a cytokine with multiple properties, is known to be rapidly inactivated in vivo. In patients with septic shock and kidney malfunction, conflicting data have been reported regarding the presence of TNF in the circulation. Recently, we have shown that these differences can be the result of the detection of free TNF vs TNF complexed with soluble TNF-R. Enhanced levels of soluble TNF-R have been reported in patients with kidney malfunction. Because the kidney is thought to play an important… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 48 extracted citations

Similar Papers

Loading similar papers…