Influence of neonatal estrogens on rat prostate development.

@article{Prins2001InfluenceON,
  title={Influence of neonatal estrogens on rat prostate development.},
  author={Gail S. Prins and Lynn Birch and H. Habermann and William Y. Chang and Christopher M. Tebeau and Oliver Putz and Charles J Bieberich},
  journal={Reproduction, fertility, and development},
  year={2001},
  volume={13 4},
  pages={
          241-52
        }
}
Brief exposure of rodents to estrogens during early development alters prostate branching morphogenesis and cellular differentiation in a dose-dependant manner. If estrogenic exposures are high, these disturbances lead to permanent imprints of the prostate, which include reduced growth, differentiation defects of the epithelial cells, altered secretory function and reduced responsiveness to androgens in adulthood. This process, referred to as neonatal imprinting or developmental estrogenization… CONTINUE READING

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