Influence of mucolytic therapy on respiratory mechanics in patients with chronic obstructive pulmonary disease.

@article{Schreiber2002InfluenceOM,
  title={Influence of mucolytic therapy on respiratory mechanics in patients with chronic obstructive pulmonary disease.},
  author={J. H. Schreiber and B Bohnsteen and W Rosahl},
  journal={European journal of medical research},
  year={2002},
  volume={7 3},
  pages={98-102}
}
Mucus hypersecretion is a hallmark of chronic obstructive pulmonary disease (COPD) and is regarded as contributing to airflow limitation in these patients. The value of mucolytic therapy is still a matter for debate. We investigated the short-term influence of an inhalative mucolytic drug mercapto-ethane sulfonate (Mesna) on the lung function, respiratory mechanics and viscous respiratory load in patients with COPD in a randomized, placebo controlled, double-blind, cross-over study in 10… CONTINUE READING

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