Influence of modifying agents on enzyme inactivation studies. An analysis using a series mechanism and a form of the Hill-type equations.


A series deactivation model is utilized to theoretically examine the influence of different modifying agents on enzyme deactivation kinetics. A form of the Hill-type equation is used to describe the effect of the modifying agents on the model parameters. Modification-induced inactivation equations are presented for the acetylation and succinylation of E… (More)