Influence of microRNAs and Long Non-Coding RNAs in Cancer Chemoresistance

@inproceedings{Ayers2017InfluenceOM,
  title={Influence of microRNAs and Long Non-Coding RNAs in Cancer Chemoresistance},
  author={Duncan Ayers and Jo Vandesompele},
  booktitle={Genes},
  year={2017}
}
Innate and acquired chemoresistance exhibited by most tumours exposed to conventional chemotherapeutic agents account for the majority of relapse cases in cancer patients. Such chemoresistance phenotypes are of a multi-factorial nature from multiple key molecular players. The discovery of the RNA interference pathway in 1998 and the widespread gene regulatory influences exerted by microRNAs (miRNAs) and other non-coding RNAs have certainly expanded the level of intricacy present for the… CONTINUE READING
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