Influence of micro-mixing on the size of liposomes self-assembled from miscible liquid phases.

  title={Influence of micro-mixing on the size of liposomes self-assembled from miscible liquid phases.},
  author={Sopan M Phapal and P. Sunthar},
  journal={Chemistry and physics of lipids},
Ethanol injection and variations of it are a class of methods where two miscible phases-one of which contains dissolved lipids-are mixed together leading to the self-assembly of lipid molecules to form liposomes. This method has been suggested, among other applications, for in situ synthesis of liposomes as drug delivery capsules. However, the mechanism that leads to a specific size selection of the liposomes in solution based self-assembly in general, and in flow-focussing microfluidic devices… CONTINUE READING
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