Influence of malnutrition on the prevalence of bacterial translocation and spontaneous bacterial peritonitis in experimental cirrhosis in rats.

@article{Casafont1997InfluenceOM,
  title={Influence of malnutrition on the prevalence of bacterial translocation and spontaneous bacterial peritonitis in experimental cirrhosis in rats.},
  author={Fernando Casafont and El{\'i}sabet S{\'a}nchez and Lester Martin and Jes{\'u}s Ag{\"u}ero and Fabiola Romero},
  journal={Hepatology},
  year={1997},
  volume={25 6},
  pages={1334-7}
}
Bacterial translocation (BT) has been involved in the pathogenesis of spontaneous bacterial peritonitis (SBP) in experimental cirrhosis. Because malnutrition is a common feature in cirrhosis, the aim of this study was to evaluate the effect of nutrition on BT and SBP. We induced cirrhosis in 44 Sprague-Dawley rats by administration of oral CCl4, and, afterward, 26 animals were maintained with dietary restriction. Cultures of mesenteric lymph nodes (MLN), peripheral and portal blood, liver, and… CONTINUE READING