Corpus ID: 202717665

Influence of magnolol on GAD 67 and GAD 65 in the hippocampus of rats with epilepsy-depression comorbidity

  title={Influence of magnolol on GAD 67 and GAD 65 in the hippocampus of rats with epilepsy-depression comorbidity},
  author={Juanjuan Shi and Jiarui Zhang and Zhuo Yuan and Li Shen and Hong Yan},
Objective: The aim of this study was to investigate the protective effects of magnolol on model rats with epilepsy-depression comorbidity, examining its influences on expression of glutamate decarboxylase 67 (GAD67) and GAD65 in the hippocampus of rats. Methods: Lithium chloride-pilocarpine was used to establish the rat model of epilepsy-depression comorbidity. At 6 weeks after modeling, the rats were randomly divided into 6 groups: control group, model group, citalopram group, and high(H… Expand

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