Influence of magnesium deficiency on the bioavailability and tissue distribution of iron in the rat.

@article{SanchezMorito2000InfluenceOM,
  title={Influence of magnesium deficiency on the bioavailability and tissue distribution of iron in the rat.},
  author={Nuria Sanchez-Morito and Elena Planells and Pilar Aranda and Juan Llopis},
  journal={The Journal of nutritional biochemistry},
  year={2000},
  volume={11 2},
  pages={
          103-8
        }
}
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32 Citations
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Background Citations
14
Methods Citations
3
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32 Citations

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Effect of magnesium deficiency on enterocyte Ca, Fe, Cu, Zn, Mn and Se content
TLDR
The Mg-deficient diet significantly increased enterocyte content of Ca, Fe, Zn, Cu and Mn; however, the authors found no significant changes in the Se content of these cells; these data support the results obtained by indirect methods.
Effect of Magnesium Deficiency on Various Mineral Concentrations in Rat Liver
TLDR
This study is the first research indicating the changes of hepatic Ga, Y, Zr, Mo, Rh, Ag, Ba, Sc, and Nb concentrations in Mg-deficient rats, and indicates that the semiquantitative analysis with ICP-MS is a valid method for screening analysis to investigate various mineral concentrations in animal tissues.
Low magnesium diet alters distribution of macroelements and trace elements in tissues and organs of female rats.
  • A. Zheltova, M. Kharitonova, A. Skalny
  • Medicine, Biology
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements
  • 2017
The Effects of Magnesium Deficiency on Molybdenum Metabolism in Rats
TLDR
Mg deficiency decreases urinary Mo excretion, which is too slight to affect plasma Mo concentration, and that Mg deficiency selectively disturbs the homeostatic mechanism of Mo in the liver, which was not related to the mRNA expression of MOT2 in the Liver.
Bioavailability, tissue distribution and hypoglycaemic effect of vanadium in magnesium-deficient rats.
TLDR
Interactions between magnesium and vanadium in the digestive and renal systems are shown and treatment with vanadium to magnesium-deficient rats corrected many of the alterations that had been generated by the magnesium deficiency.
Short-term dietary magnesium restriction lowers spleen iron concentrations in growing rats fed a high-fat diet
Influence of graded magnesium deficiencies on white blood cell counts and lymphocyte subpopulations in rats.
TLDR
A threshold effect for increased leukocytes during a Mg deficiency of four weeks is demonstrated, demonstrating the influence that acute and moderate Mg deficiencies have on bloodLeukocytes at high and low dietary phosphorus levels.
Evaluation of the level of selected iron-related proteins/receptors in the liver of rats during separate/combined vanadium and magnesium administration.
Effects of source and level of magnesium on catalase activity and its gene expression in livers of broiler chickens
TLDR
It can be concluded that dietary Mg supplementation could increase hepatic Mg concentration, enhance CAT mRNA expression and consequently enhance CAT activity, and the organic Mg (MgAsp or MgdiAsp) is much more efficient than the inorganic form ( MgO).
Hepcidin expression in the liver of rats fed a magnesium-deficient diet
TLDR
Accumulation of hepatic Fe by Mg deficiency is a stimulant inducing Bmp6 expression but not Hepcidin expression by blunting Bmp signalling possibly resulting from down-regulation of the receptor expression, which indicates that unresponsive HepcIDin expression may have a role in M g deficiency-induced changes related to increased liver Fe.
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References

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Changes in bioavailability and tissue distribution of copper caused by magnesium deficiency in rats
TLDR
It is shown that chronic Mg deficiency increases Cu absorption and the concentrations of this mineral in plasma, muscle, kidney, and liver in Wistar rats after 7, 35, 49, and 70 days.
On the origin of the increased tissue iron content in graded magnesium deficiency states in the rat
TLDR
Hemolytic anaemia developed because even the high erythropoietic activity in the 70 and 110 mg Mg/kg groups was not sutlicient to recycle all haemoglobin Fe liberated by haemolysis, indicating that the excess of liberated haemobic Fe was stored in the tissue.
Changes in bioavailability and tissue distribution of zinc caused by magnesium deficiency in rats
TLDR
The effect of a Mg-deficient diet on the bioavailability of dietary Zn and the concentration of this cation in plasma, whole blood, skeletal muscle, kidney, heart and brain of Wistar rats was studied and no change was found in brain Zn concentration.
Effect of magnesium deficiency on fatty acid composition of the erythrocyte membrane and plasma lipid concentration in rats
Changes in tissue calcium and phosphorus content and plasma concentrations of parathyroid hormone and calcitonin after long-term magnesium deficiency in rats.
TLDR
PTH appeared to be more closely related with hypomagnesemia than with hypercalcemia, and decreased P levels in blood, heart, and femur.
Evolution of Mg deficiency in rats.
TLDR
The results generally showed an increase in digestive utilization and a decrease in Mg balance during the experimental period, whereas renal Mg concentration tended to rise slightly during the last 2 weeks of study.
The absorption of iron, calcium, phosphorus, magnesium, copper and zinc in the jejunum–ileum of control and iron-deficient rats
TLDR
Iron absorption in anaemic rats was greater than in the controls, except after perfusion with solutions containing haemoglobin, and the absorption values of calcium, copper and zinc were lower than after ferric citrate in both groups (control and iron-deficient rats).
Increased lipid peroxidation in liver mitochondria from Mg-deficient rats.
TLDR
Feeding young rats an Mg-deficient diet for 4 weeks increased serum-Fe concentration and non Hb-Fe content in liver and this may be involved in the increased lipid peroxidation of liver mitochondria, but cannot represent a general mechanism in the toxicity of Mg deficiency.
The hemolytic anemia of magnesium deficiency in adult rats.
TLDR
In vitro synthesis of heme and globin, as measured with 14C-glycine was the same as in control rats with "reticulocytosis-rich" anemia produced by bleeding or immunologically.
Effects of Copper and Zinc Status of Rats on Erythrocyte Stability and Superoxide Dismutase Activity 1
TLDR
Erythrocytes from zinc deficient rats, which had low plasma zinc and high plasma copper (low Zn:Cu), were more fragile than those from controls, and SOD activity is suggested as a clinical index of tissue copper status.
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