Influence of liposphere preparation on butyl-methoxydibenzoylmethane photostability.

  title={Influence of liposphere preparation on butyl-methoxydibenzoylmethane photostability.},
  author={Valentina Iannuccelli and Nicoletta Sala and Rosanna Tursilli and Gilberto Coppi and Santo Scalia},
  journal={European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V},
  volume={63 2},
The incorporation of butyl-methoxydibenzoylmethane (BMDBM), one of the most efficient and frequently used UV-A blockers, into lipospheres was examined in order to decrease the light-induced sunscreen degradation. Lipospheres, obtained by the melt technique and using tristearin as the lipid material and hydrogenated phosphatidylcholine as the emulsifier, showed proper features in terms of size (10-40 microm), BMDBM loading level (21.63% +/- 0.90%, w/w) and physical state. Photolysis studies… CONTINUE READING