Influence of intraperitoneal application of taurolidine/heparin on expression of adhesion molecules and colon cancer in rats undergoing laparoscopy.

@article{Bobrich2007InfluenceOI,
  title={Influence of intraperitoneal application of taurolidine/heparin on expression of adhesion molecules and colon cancer in rats undergoing laparoscopy.},
  author={Eva Bobrich and Chris Braumann and Isabelle Opitz and Charalambos Menenakos and Glen Kristiansen and Christoph Andreas Jacobi},
  journal={The Journal of surgical research},
  year={2007},
  volume={137 1},
  pages={
          75-82
        }
}
BACKGROUND Recent experimental studies have shown that intraperitoneal administration of taurolidine/heparin causes a reduction of local tumor growth after laparoscopy in rat models. It might be that the anti-adherent activities of these agents are responsible for this effect. In this study we investigated the adhesion molecules E-cadherin, beta1-integrin, and CD44. MATERIALS AND METHODS Following a 10,000 colon adenocarcinoma cells' (DHD/K12/TRb) intraperitoneal application a cecum resection… CONTINUE READING
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