Influence of interleukin-6 and G174C polymorphism in IL-6 gene on obesity and energy balance

  title={Influence of interleukin-6 and G174C polymorphism in IL-6 gene on obesity and energy balance},
  author={Katarzyna Popko and E. G{\'o}rska and Urszula Demkow},
  booktitle={European journal of medical research},
Obesity is a multifactor disease with a very complicated etiology. Genetic factors play an important role in the development of primary obesity. They may be responsible for up to 40% of causes leading to obesity. There are a great number of genes affecting food intake and energy expenditure. Serious consequences accompanying obesity, e.g., type 2 diabetes and lipid abnormalities may be caused by increased level of proinflammatory cytokines, such as IL-1, IL-6, and TNF. It is possible that… CONTINUE READING


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