• Corpus ID: 24308199

Influence of insulin on pharmacokinetics of mannosulfan in rats.

@article{Danysz1979InfluenceOI,
  title={Influence of insulin on pharmacokinetics of mannosulfan in rats.},
  author={Andrzej Danysz and M. Wutkiewicz and Karol Wierzba},
  journal={Archivum immunologiae et therapiae experimentalis},
  year={1979},
  volume={27 3},
  pages={
          377-81
        }
}
The purpose of the present study was to investigate the possibilities of potentiation of the antitumor action of mannosulfan after its administration together with insulin. The pharmacokinetics of mannnosulfan were investigated after its administration separately and together with insulin. Concentrations of mannosulfan in the plasma were determined by gas chromatography. Insulin enhanced the rate of absorption of mannosulfan from the peritoneal cavity and prolonged its elimination from the body… 
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