Influence of insulin-like growth factors on the strength of the relation of vitamin D and calcium intakes to mammographic breast density.

@article{Diorio2006InfluenceOI,
  title={Influence of insulin-like growth factors on the strength of the relation of vitamin D and calcium intakes to mammographic breast density.},
  author={Caroline Diorio and Sylvie B{\'e}rub{\'e} and Celia Byrne and Beno{\^i}t M{\^a}sse and Nicole H{\'e}bert-croteau and Martin Joel Yaffe and Gary C{\^o}t{\'e} and Michael Pollak and Jacques Brisson},
  journal={Cancer research},
  year={2006},
  volume={66 1},
  pages={
          588-97
        }
}
Diets with higher vitamin D and calcium contents were found associated with lower mammographic breast density and breast cancer risk in premenopausal women. Because laboratory studies suggest that the actions of vitamin D, calcium, insulin-like growth factor (IGF)-I, and IGF-binding protein-3 (IGFBP-3) on human breast cancer cells are interrelated, we examined whether IGF-I and IGFBP-3 levels could affect the strength of the association of vitamin D and calcium intakes with breast density… CONTINUE READING

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