Influence of imprinting with A and B chains of insulin on binding and functional changes in tetrahymena.

Abstract

Insulin and its A and B chain increased the quantity of intracellular PAS-positive material (glycogen) in tetrahymena, whereas the combined A + B chains decreased it. Imprinting--previous interaction--with insulin, its A and B chains in themselves and with the A + B chain increased the hormone binding capacity of tetrahymena, but the functional effect of… (More)