Influence of hypoxia and hypercapnia on sleep state-dependent heart rate variability behavior in newborn lambs.

@article{Beuchee2012InfluenceOH,
  title={Influence of hypoxia and hypercapnia on sleep state-dependent heart rate variability behavior in newborn lambs.},
  author={Alain Beuchee and Alfredo I. Hern{\'a}ndez and Charles Duvareille and David E. Daniel and Nathalie Samson and Patrick Pladys and Jean-Paul Praud},
  journal={Sleep},
  year={2012},
  volume={35 11},
  pages={1541-9}
}
STUDY OBJECTIVES Although hypercapnia and/or hypoxia are frequently present during chronic lung disease of infancy and have also been implicated in sudden infant death syndrome (SIDS), their effect on cardiac autonomic regulation remains unclear. The authors' goal is to test that hypercapnia and hypoxia alter sleep-wake cycle-dependent heart rate variability (HRV) in the neonatal period. DESIGN Experimental study measuring HRV during sleep states in lambs randomly exposed to hypercapnia… CONTINUE READING
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