Influence of hydrocortisone on the modulation of the inflammatory response.

Abstract

In vitro hydrocortisone, in pharmacologically attainable concentrations, binds nonspecifically to rat peritoneal mast cells and amplifies the stimulating effects of PGE1 on membrane-bound adenylate cyclase. As a consequence, the intracellular concentration of cyclic AMP in the target cells increases and histamine release is markedly reduced… (More)

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Cite this paper

@article{Tolone1978InfluenceOH, title={Influence of hydrocortisone on the modulation of the inflammatory response.}, author={G. Tolone and Lara K Bonasera and Carlo Tolone}, journal={British journal of experimental pathology}, year={1978}, volume={59 4}, pages={366-72} }