Influence of growth hormone on the craniofacial complex of transgenic mice.

@article{RamirezYaez2005InfluenceOG,
  title={Influence of growth hormone on the craniofacial complex of transgenic mice.},
  author={German Omar Ramirez-Ya{\~n}ez and Joseph R Smid and William George Young and Michael J. Waters},
  journal={European journal of orthodontics},
  year={2005},
  volume={27 5},
  pages={494-500}
}
Growth hormone (GH) secretion affects bone and cartilage physiology. This study investigated the effect of GH on the size of the craniofacial structures and their angular relationship. Three different models of mice with a genetically altered GH axis were used: GH excess (giant), dwarf GH antagonist (dwarf-Ant), and dwarf GH receptor knockout (dwarf-KO) mice. Each model was compared with the corresponding wild type (Wt). Five craniofacial distances were analysed: craniofacial length, upper face… CONTINUE READING

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