Influence of glycogen storage on vascular smooth muscle metabolism.

  title={Influence of glycogen storage on vascular smooth muscle metabolism.},
  author={Theodore J. Allen and Christopher D. Hardin},
  journal={American journal of physiology. Heart and circulatory physiology},
  volume={278 6},
The role of glycogen as an oxidative substrate for vascular smooth muscle (VSM) remains controversial. To elucidate the importance of glycogen as an oxidative substrate and the influence of glycogen flux on VSM substrate selection, we systematically altered glycogen levels and measured metabolism of glucose, acetate, and glycogen. Hog carotid arteries with glycogen contents ranging from 1 to 11 micromol/g were isometrically contracted in physiological salt solution containing 5 mM [1-(13)C… CONTINUE READING


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