Influence of glucose on production and N-sulfation of heparan sulfate in cultured adipocyte cells

@article{Parthasarathy2000InfluenceOG,
  title={Influence of glucose on production and N-sulfation of heparan sulfate in cultured adipocyte cells},
  author={Narayanan Parthasarathy and Lisa F. Gotow and James D. Bottoms and Joseph C. Obunike and Annamaria Naggi and Benito Casu and Ira J Goldberg and William D. Wagner},
  journal={Molecular and Cellular Biochemistry},
  year={2000},
  volume={213},
  pages={1-9}
}
Altered lipoprotein lipase regulation associated with diabetes leading to the development of hypertriglyceridemia might be attributed to possible changes in content and the fine structure of heparan sulfate and its associated lipoprotein lipase. Adipocyte cell surface is the primary site of synthesis of lipoprotein lipase and the enzyme is bound to cell surface heparan sulfate proteoglycans via heparan sulfate side chains. In this study, the effect of diabetes on the production of adipocyte… CONTINUE READING
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