Influence of glucosamine on the uptake of nucleosides by chick fibroblasts and on the incorporation into RNA.

@article{Scholtissek1972InfluenceOG,
  title={Influence of glucosamine on the uptake of nucleosides by chick fibroblasts and on the incorporation into RNA.},
  author={Christoph Scholtissek},
  journal={Biochimica et biophysica acta},
  year={1972},
  volume={277 3},
  pages={
          459-65
        }
}
  • C. Scholtissek
  • Published 14 September 1972
  • Chemistry, Medicine
  • Biochimica et biophysica acta
Abstract As a consequence of the reduction of the UTP pool by glucosamine the velocity of the uptake of uridine into the cells is drastically increased. Since the same effect is observed for the uptake of cytidine but not of adenosine, it is concluded that UTP (or a derivative of it) acts in vivo by negative feedback on the pyrimidine nucleoside kinase or a common transport system. After increasing the UTP or CTP pools the velocity of the uptake of both pyrimidine nucleosides is markedly… Expand
Effect of ethanol on the transport of nucleosides into primary chick fibroblasts
Abstract Ethanol interferes with the uptake of uridine into tissue culture cells more severely than with the uptake of adenosine. RNA synthesis is not impaired. The effect of ethanol is completelyExpand
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The depletion of circulating cytidine in the presence of hepatocellular UTP deficiency points to the importance of the liver and the hepatic UTP level for the clearance of blood plasma cytidine. Expand
Inhibition of the multiplication of enveloped viruses by glucose derivatives.
  • C. Scholtissek
  • Chemistry, Medicine
  • Current topics in microbiology and immunology
  • 1975
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