Influence of glucogenic amino acids on the hepatic metabolism of threonine.

@article{Moundras1992InfluenceOG,
  title={Influence of glucogenic amino acids on the hepatic metabolism of threonine.},
  author={Corinne Moundras and David Bercovici and Christian R{\'e}m{\'e}sy and Christian Demign{\'e}},
  journal={Biochimica et biophysica acta},
  year={1992},
  volume={1115 3},
  pages={212-9}
}
The supplementation of a low-protein diet with L-threonine leads to a marked accumulation of threonine in plasma and liver, whereas increasing dietary protein generally leads to an induction of threonine dehydratase in the liver, hence depressed availability for extrasplanchnic tissues. The aim of the present study was, thus, to further investigate the factors which control the utilization of threonine by the liver. Increasing the dietary supply of threonine led to parallel increases in the… CONTINUE READING