Influence of genetic background and gender on bladder function in the mouse.

@article{Cornelissen2008InfluenceOG,
  title={Influence of genetic background and gender on bladder function in the mouse.},
  author={Laura L Cornelissen and Blake A Misajet and David P. Brooks and Alexandra Hicks},
  journal={Autonomic neuroscience : basic & clinical},
  year={2008},
  volume={140 1-2},
  pages={53-8}
}
Genetically targeted animals are used throughout research to investigate the role genes play in biological function, including the lower urinary tract. Generation of transgenic mice involves backcrossing for successive generations. Parental strain background genes can interact with the mutated gene potentially affecting interpretation of the mutant phenotype. Differences in physiological phenotypes may also be influenced by gender. The present study evaluated bladder function in five strains of… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
11 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…