Influence of formulation parameters on gadolinium entrapment and tumor cell uptake using folate-coated nanoparticles.

@article{Oyewumi2003InfluenceOF,
  title={Influence of formulation parameters on gadolinium entrapment and tumor cell uptake using folate-coated nanoparticles.},
  author={Moses O. Oyewumi and Russell J. Mumper},
  journal={International journal of pharmaceutics},
  year={2003},
  volume={251 1-2},
  pages={
          85-97
        }
}
  • M. Oyewumi, R. Mumper
  • Published 30 January 2003
  • Chemistry, Biology
  • International journal of pharmaceutics
Gadolinium incorporated reconstituted chylomicron emulsion for potential application in tumor neutron capture therapy.
  • Annie M Dierling, Brian R. Sloat, Z. Cui
  • Biology
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
  • 2006
Albumin-based nanoparticles as potential controlled release drug delivery systems.
Cationic bovine serum albumin (CBA) conjugated poly lactic-co-glycolic acid (PLGA) nanoparticles for extended delivery of methotrexate into brain tumors
TLDR
The outcomes of the study evidently indicate the prospect of CBA conjugated poly (D,L-lactide-co-glycolide) (PLGA) NPs loaded with MTX in a brain cancer bomber, with the amplified capability to circumvent the BBB.
Enhanced oral bioavailability of daidzein by self-microemulsifying drug delivery system.
TLDR
Self-microemulsifying drug delivery system (SMEDDS) composed of oil, surfactant and cosurfactant for oral administration of daidzein was formulated and its physicochemical properties and pharmacokinetic parameters were evaluated.
Development of nanostructured lipid carriers (NLC) for controlled delivery of meloxicam
Nanostructured lipid carriers (NLC) are becoming increasingly popular due to their obvious advantages over other existing lipid based carriers. They have improved drug encapsulation efficiency and
...
...

References

SHOWING 1-10 OF 35 REFERENCES
Gadolinium-Loaded Nanoparticles Engineered from Microemulsion Templates
TLDR
The ease of preparation of these very small and stable nanoparticles, and the ability to entrap lipophilic drugs such as GdAcAc with high efficiency, suggested that these systems may have potential in cell targeting, especially for specific delivery to tumor cells for NCT.
Engineering tumor-targeted gadolinium hexanedione nanoparticles for potential application in neutron capture therapy.
TLDR
The results suggested that these tumor-targeted nanoparticles containing high concentrations of Gd may have potential for neutron capture therapy.
Chitosan-Gadopentetic Acid Complex Nanoparticles for Gadolinium Neutron-Capture Therapy of Cancer: Preparation by Novel Emulsion-Droplet Coalescence Technique and Characterization
TLDR
Gd-nanoCPs might be useful as an i.t. injectable device for gadolinium neutron-capture therapy and their ability for long-term retention of Gd-DTPA in the tumor indicated that.
Preparation of lecithin microcapsules by a dilution method using the Wurster process for intraarterial administration in gadolinium neutron capture therapy.
TLDR
Administration of these microcapsules might be multiply repeated in order to accumulate the required amount of Gd in tumors in neutron capture therapy.
Solid lipid nanoparticles (SLN) : an alternative colloidal carrier system for controlled drug delivery
TLDR
Solid lipid nanoparticles of optimized composition proved to be physically stable during sterilization (autoclaving) and on long-term as aqueous dispersion as well as in vitro drug release over 5 weeks (prednisolone).
Body distribution in mice of intravenously injected camptothecin solid lipid nanoparticles and targeting effect on brain.
Design of folic acid-conjugated nanoparticles for drug targeting.
TLDR
Folate-linked nanoparticles represent a potential new drug carrier for tumor cell-selective targeting in PEG-coated biodegradable nanoparticles coupled to folic acid to target the folate-binding protein.
Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art.
  • R. Müller, K. Mäder, S. Gohla
  • Chemistry
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
  • 2000
...
...