Influence of food on pharmacokinetics of zolpidem from fast dissolving sublingual zolpidem tartrate tablets

@article{Greenblatt2013InfluenceOF,
  title={Influence of food on pharmacokinetics of zolpidem from fast dissolving sublingual zolpidem tartrate tablets},
  author={D. Greenblatt and J. Harmatz and Nikhilesh N. Singh and T. Roth and S. Harris and R. Kapil},
  journal={The Journal of Clinical Pharmacology},
  year={2013},
  volume={53}
}
Ingesting food can impact the pharmacokinetics of sedative‐hypnotic drugs. A buffered zolpidem sublingual tablet (ZST) recently became available for the treatment of middle‐of‐the‐night awakening. In this randomized, open‐label, single‐site study, the pharmacokinetic profile of ZST was evaluated when administered while fasting and following a standard high‐fat meal (fed state). Healthy adults aged 18–64 years received a single morning dose of 3.5 mg ZST in the fed or fasting state. From 20 min… Expand
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