Influence of food on bioavailability from two controlled-release granules of theophylline.

@article{Tada1989InfluenceOF,
  title={Influence of food on bioavailability from two controlled-release granules of theophylline.},
  author={Hitoshi Tada and Masaaki Ishikawa and Eisaku Sato and Toshio Suzuki and Keiko Unno and Kyoko Miura and Yoshihiro Ohmiya and Kunihiro Nakai},
  journal={Journal of clinical pharmacy and therapeutics},
  year={1989},
  volume={14 2},
  pages={145-51}
}
The bioavailability and absorption pattern of theophylline from Theolong granule and Theodur-G were studied in five healthy volunteers both in fasting conditions and after taking two different meals. In all the subjects, no dose-dumping effect was observed with a standard- or a fat-rich breakfast on these preparations. Postprandial administration delayed… CONTINUE READING