Influence of experimental diabetes on sarcoplasmic reticulum function in rat ventricular muscle.

Abstract

We examined whether the decrease in cardiac contractility in streptozotocin-induced diabetes in the rat is accompanied by reduced or excessive loading of the sarcoplasmic reticulum (SR) with Ca2+. Pooled SR Ca2+ content and fractional release on stimulation were estimated with rapid cooling contracture (RCC) and twitch height measurements, respectively… (More)

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@article{Bouchard1991InfluenceOE, title={Influence of experimental diabetes on sarcoplasmic reticulum function in rat ventricular muscle.}, author={R A Bouchard and Debanjan Bose}, journal={The American journal of physiology}, year={1991}, volume={260 2 Pt 2}, pages={H341-54} }