Influence of ethanol on pancreatic lipid metabolism.

  title={Influence of ethanol on pancreatic lipid metabolism.},
  author={J B Somer and Gilbert Thompson and Romano Cesare Pirola},
  journal={Alcoholism, clinical and experimental research},
  volume={4 4},
The influence of acute exposure to ethanol on rat pancreatic lipogenesis has been investigated. Marked alterations of in vitro pancreatic lipid metabolism were found with changes compatible with increased de novo triglyceride synthesis. Ethanol in vitro stimulated (U--14C) glucose incorporation into triglyceride, but inhibited incorporation into phosphatidyl choline. Prior exposure to ethanol did not further enhance these effects on labeled glucose incorporation. One hour after feeding ethanol… CONTINUE READING