Influence of engineered nanoparticles from metals on the blood-brain barrier permeability, cerebral blood flow, brain edema and neurotoxicity. An experimental study in the rat and mice using biochemical and morphological approaches.

@article{Sharma2009InfluenceOE,
  title={Influence of engineered nanoparticles from metals on the blood-brain barrier permeability, cerebral blood flow, brain edema and neurotoxicity. An experimental study in the rat and mice using biochemical and morphological approaches.},
  author={Hari Shanker Sharma and S. Fatehyab Ali and Saber M. Hussain and John J. Schlager and Aruna Sharma},
  journal={Journal of nanoscience and nanotechnology},
  year={2009},
  volume={9 8},
  pages={
          5055-72
        }
}
Influence of nanoparticles on brain function following in vivo exposures is not well known. Depending on the magnitude and intensity of nanoparticle exposure from the environment, food and/or water source, neuronal function could be affected and may lead to neurotoxicity and neuropathology. This hypothesis was examined in present investigation using systemic or intracerebroventricular administration of engineered nanoparticles from metals, i.e., Al, Ag and Cu (approximately equal to 50 to 60 nm… CONTINUE READING

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