Influence of endogenous oestrogens on QT interval duration.

  title={Influence of endogenous oestrogens on QT interval duration.},
  author={J. C. Hulot and J. M. Demolis and R. Dujarric de la Rivi{\`e}re and Soraya Strabach and Sophie Christin-Ma{\^i}tre and Christian Funck-Brentano},
  journal={European heart journal},
  volume={24 18},
AIMS Women have a longer QT interval and a greater incidence of torsades de pointes than men. It has been suggested that oestrogens may influence the duration of cardiac repolarization. We thus investigated the influence of oestradiol (E2) on ventricular repolarization within the physiological concentration range of this hormone. METHODS AND RESULTS We studied QT interval duration in 21 healthy women aged 18 to 35 years with regular menstrual cycle (mean duration: 29+/-1 days) during two… CONTINUE READING