Influence of ellagic acid on antioxidant defense system and lipid peroxidation in mice.

@article{Majid1991InfluenceOE,
  title={Influence of ellagic acid on antioxidant defense system and lipid peroxidation in mice.},
  author={Samara Majid and Krishan Lal Khanduja and Rahul Gandhi and Sanjay Kapur and Rakesh Raman Sharma},
  journal={Biochemical pharmacology},
  year={1991},
  volume={42 7},
  pages={1441-5}
}
Addition of ellagic acid (EA) to liver microsomes of mice resulted in a steady increase in inhibition of NADPH-dependent lipid peroxidation up to 2 mM concentration. The maximum of 70% inhibition of ascorbate-dependent lipid peroxidation was achieved at 1 mM concentration of EA. Feeding of EA significantly increased the levels of reduced glutathione and glutathione reductase in liver and lungs of male and female mice. However, there were no changes in the activities of catalase and superoxide… CONTINUE READING

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