Influence of dual blockade of the renin-angiotensin system on thirst in hemodialysis patients.

BACKGROUND/AIMS Angiotensin II promotes sodium retention and influences the central regulation of fluid intake. Clinical studies on the effect of an angiotensin-converting enzyme inhibitor (ACEI) on xerostomia and thirst in chronic hemodialysis (HD) patients were scarce and gave contradictory results. We hypothesized that a more effective inhibition of the… (More)