Influence of dose-rate and dose per fraction on clinical outcome of breast cancer treated by external beam irradiation plus iridium-192 implants: analysis of 289 cases.

@article{Deore1993InfluenceOD,
  title={Influence of dose-rate and dose per fraction on clinical outcome of breast cancer treated by external beam irradiation plus iridium-192 implants: analysis of 289 cases.},
  author={Shivaji Deore and Rajiv Sarin and Ketayun Ardeshir Dinshaw and Shyam Kishore Shrivastava},
  journal={International journal of radiation oncology, biology, physics},
  year={1993},
  volume={26 4},
  pages={601-6}
}
PURPOSE To study the influence of Iridium 192 implant dose-rate and dose per fraction of external irradiation on clinical outcome, the results in 289 patients with early breast cancer were analyzed retrospectively. METHODS AND MATERIALS From 1980 to 1990, 118 T1 and 171 T2 lesions of breast were treated definitively by radiotherapy, following conservative surgery. External irradiation dose of 45 Gy was delivered either with 2.5 Gy or 1.8 Gy per fraction to the entire target volume, plus boost… CONTINUE READING
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