Influence of direct current on the electrical activity of the heart and on its susceptibility to ventricular fibrillation


Isolated perfused guinea pig hearts (Langendorff preparation) were used to study the influence of direct current (DC) on the shape of the electrogram and to determine the thresholds for extrasystoles and for fibrillation. DC impulse durations ranged between 30 ms and 5 s. During DC flow through the heart, marked deformations of the electrogram occur mainly… (More)
DOI: 10.1007/BF01908039


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