Influence of dietary charcoal on ochratoxin A toxicity in Leghorn chicks.

@article{Rotter1989InfluenceOD,
  title={Influence of dietary charcoal on ochratoxin A toxicity in Leghorn chicks.},
  author={R G Rotter and Andrew A Frohlich and Ronald R. Marquardt},
  journal={Canadian journal of veterinary research = Revue canadienne de recherche veterinaire},
  year={1989},
  volume={53 4},
  pages={449-53}
}
The ability of activated charcoal to adsorb ochratoxin A (OA) in vitro and to reduce the toxic effects of OA in vivo when added to the diet of growing Leghorn chicks was studied. Activated charcoal (50 mg) was able to adsorb 90% of the OA (150 micrograms) contained in 10 mL of citrate-phosphate buffer (pH 7.0). When 2 g of a complete chick diet were mixed with OA in buffer, it adsorbed 66% of the OA, while addition of 50 mg of charcoal to this mixture further reduced the concentration of OA to… CONTINUE READING

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