Influence of dexamethasone on nocturnal melatonin production in healthy adult subjects.

@article{Demisch1988InfluenceOD,
  title={Influence of dexamethasone on nocturnal melatonin production in healthy adult subjects.},
  author={Lothar Demisch and K. Demisch and T Nickelsen},
  journal={Journal of pineal research},
  year={1988},
  volume={5 3},
  pages={317-22}
}
There is no conclusive evidence supporting an interaction between the pineal gland and the hypothalamic-pituitary-adrenal axis. In this study, 11 healthy adults (six women, five men; aged 18-47 years) received a placebo the first night and 1 mg dexamethasone the next night at either 1800 or 2300 h. Administration of 1 mg of dexamethasone was followed by an attenuation of the nocturnal production of melatonin in 9 of 11 subjects. A significant reduction was found between melatonin plasma levels… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
17 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 17 extracted citations

Similar Papers

Loading similar papers…