Influence of collagen network on left ventricular systolic and diastolic function in aortic valve disease.

@article{Villari1993InfluenceOC,
  title={Influence of collagen network on left ventricular systolic and diastolic function in aortic valve disease.},
  author={Bruno Villari and Scott E. Campbell and Otto Martin Hess and Gerhard Mall and Giuseppe Vassalli and Karl T. Weber and Hans P. Krayenb{\"u}hl},
  journal={Journal of the American College of Cardiology},
  year={1993},
  volume={22 5},
  pages={1477-84}
}
OBJECTIVES The purpose of this study was to evaluate left ventricular structure-function interplay in aortic valve disease. BACKGROUND An increase in myocardial fibrosis has been demonstrated in aortic valve disease, but changes in the collagen network and their effect on ventricular function have not been defined. METHODS Left ventricular structure was assessed from left ventricular endomyocardial biopsy specimens obtained in 32 patients with aortic valve disease (aortic stenosis in 25… CONTINUE READING
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