Influence of collagen gel substratum on response to low-density lipoprotein by cultured human skin fibroblasts.

@article{Hoover1988InfluenceOC,
  title={Influence of collagen gel substratum on response to low-density lipoprotein by cultured human skin fibroblasts.},
  author={G A Hoover and Sally McCormick and Norman Kalant},
  journal={Biochemistry and cell biology = Biochimie et biologie cellulaire},
  year={1988},
  volume={66 2},
  pages={116-25}
}
The effect of low-density lipoprotein (LDL) on accumulation of glycosaminoglycans (GAG) was compared in cultures of human skin fibroblasts on a conventional plastic substratum and in a native type I collagen gel. The 24-h incorporation of [3H]glucosamine and Na2(35)SO4 into GAG secreted into the medium or associated with the substratum and cell surface (SCA… CONTINUE READING