Influence of collagen gel on the orientation of epithelial cell polarity: follicle formation from isolated thyroid cells and from preformed monolayers

@article{Chambard1981InfluenceOC,
  title={Influence of collagen gel on the orientation of epithelial cell polarity: follicle formation from isolated thyroid cells and from preformed monolayers},
  author={Marianne Chambard and Jacqueline Gabrion and Jean Mauchamp},
  journal={The Journal of Cell Biology},
  year={1981},
  volume={91},
  pages={157 - 166}
}
The influence of collagen gels on the orientation of the polarity of epithelial thyroid cells in culture was studied under four different conditions. (a) Isolated cells cultured on the surface of a collagen gel formed a monolayer. The apical pole was in contact with the culture medium and the basal membrane was attached to the substratum. (b) Isolated cells embedded inside the gel organized within 8 into follicles. The basal pole was in contact with collagen and the apical pole was oriented… CONTINUE READING

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