Influence of clonogenic assay methodology on measurement of drug sensitivities in vitro

Abstract

To assess the influence of clonogenic assay methodology on measurement of reproductive cell kill, the in vitro sensitivities of a human bladder cancer cell line, RT112, to methotrexate and adriamycin were determined using ten different procedures. Marked differences in dose-response to methotrexate, but not adriamycin, were observed.

DOI: 10.1007/BF00255293

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Cite this paper

@article{Hepburn1986InfluenceOC, title={Influence of clonogenic assay methodology on measurement of drug sensitivities in vitro}, author={Peter J. Hepburn and John R. W. Masters}, journal={Cancer Chemotherapy and Pharmacology}, year={1986}, volume={16}, pages={80-82} }