Influence of cigarette smoking on pemphigus – a systematic review and pooled analysis of the literature

@article{Lai2018InfluenceOC,
  title={Influence of cigarette smoking on pemphigus – a systematic review and pooled analysis of the literature},
  author={Olivia Lai and Andreas Recke and Detlef Zillikens and Michael Kasperkiewicz},
  journal={Journal of the European Academy of Dermatology and Venereology},
  year={2018},
  volume={32}
}
Epidemiological evidence suggests that smoking cigarettes may be beneficial in pemphigus, but no systematic evaluation exists to corroborate this assumption. Therefore, a systematic literature review with pooled data analysis of the smoking status in patients with pemphigus was conducted. Electronic searches using PubMed from inception to November 2017 identified 13 reports meeting predetermined inclusion and exclusion criteria. Most were case–control studies partly reporting that pemphigus… 
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References

SHOWING 1-10 OF 29 REFERENCES
Risk factors in patients with oral pemphigus vulgaris: a case-control study.
TLDR
The findings indicated that cessation of smoking and HSV infection in recent weeks are risk factors for PV, while lack of occupational exposure to pesticides and increasing parity (a greater number of births) are protective factors against PV.
Pemphigus in Israel--an epidemiologic analysis of cases in search of risk factors.
TLDR
The findings show that the typical Israeli pemphigus patient is middle-aged, married, and of East European or Middle Eastern origin, and there is a possible correlation between occupational exposure to pesticides and UV radiation, and pemPHigus induction.
Pemphigus and depression comorbidity: a case control study
TLDR
The increased prevalence of depressive morbidity, especially in the presence of commonly prescribed corticosteroid treatment, emphasizes the need for psychiatric assessment and intervention in pemphigus patients.
Bipolar Disorder Associated with Another Autoimmune Disease—Pemphigus: A Population-based Study
TLDR
Pemphigus is significantly associated with bipolar disorders and should be assessed for comorbid BD, and experimental research is needed to better recognize the biological mechanisms underlying this observation.
A case of pemphigus vulgaris improved by cigarette smoking.
TLDR
A 27-year-old white man presented to the authors' clinic with a 3-year history of pemphigus vulgaris and was treated with intramuscular injections of aurothioglucose (75 mg weekly) and oral auranofin, without improvement.
Possible triggering factors and comorbidities in newly diagnosed autoimmune bullous diseases.
TLDR
Evaluation of triggering factors and comorbidities before starting treatment may assist in controlling the disease more swiftly and reducing the side effects of treatment in the management of ABDs.
Nicotine-patch therapy on mucocutaneous lesions of Behcet's disease: a case series.
TLDR
At least in ex-smokers, nicotine in its pure form is well tolerated and its use could be justified in selected cases of BD with predominant and recurrent refractory mucocutaneous manifestations.
New approaches to the treatment of pemphigus.
  • S. Grando
  • Medicine, Biology
    The journal of investigative dermatology. Symposium proceedings
  • 2004
TLDR
First results indicate that nonsteroidal treatment of pemphigus is possible and cholinomimetic Mestinon may be used to slow down progression of the disease and to treat mild cases with chronic lesions on limited areas.
Impact of smoking on pemphigus
TLDR
The aim of this case–control study was to compare the remission rate and clinical locations involved in smokers and nonsmokers with pemphigus vulgaris.
SMOKING AND SKIN
TLDR
It can be concluded that the rate of type I and III collagen synthesis in skin is decreased and the regulation of ECM turnover is altered in smokers, which may lead to deterioration of the tensile strength and resiliency of skin in the long term, even though no morphological changes were detected in the present study.
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