Influence of cholesterol on the association of plasma proteins with liposomes.

@article{Semple1996InfluenceOC,
  title={Influence of cholesterol on the association of plasma proteins with liposomes.},
  author={Sean C Semple and Arcadio Chonn and Pieter R Cullis},
  journal={Biochemistry},
  year={1996},
  volume={35 8},
  pages={2521-5}
}
The in vivo association of blood proteins with large unilamellar liposomes composed of saturated phosphatidylcholines was analyzed to determine the effect of membrane fluidity and hydrocarbon chain length on liposome-plasma protein interactions and liposome clearance. Liposomes composed of dimyristoylphosphatidylcholine (DMPC), dipalmitoylphosphatidylcholine (DPPC), distearoylphosphatidylcholine (DSPC), and diarachidoylphosphatidylcholine (DAPC) were administered via the lateral tail vein of CD… CONTINUE READING