Influence of cholesterol and ergosterol on membrane dynamics using different fluorescent reporter probes.

@article{Shrivastava2007InfluenceOC,
  title={Influence of cholesterol and ergosterol on membrane dynamics using different fluorescent reporter probes.},
  author={Sandeep Shrivastava and Amitabha Chattopadhyay},
  journal={Biochemical and biophysical research communications},
  year={2007},
  volume={356 3},
  pages={705-10}
}
Ergosterol is an evolutionary precursor of cholesterol and is the major sterol present in lower eukaryotes. Although detailed biophysical characterization of the effect of cholesterol on membranes is well documented, the effect of ergosterol on the organization and dynamics of membranes is still at a very early stage. We have monitored the effect of cholesterol and ergosterol on the dynamic properties of both fluid (POPC) and gel (DPPC) phase membranes utilizing fluorescent reporter probes… CONTINUE READING
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Determination of the orientation and dynamics of ergosterol in model membranes using uniform 13C labeling and dynamically averaged 13C chemical shift anisotropies as experimental restraints

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