Influence of cholesterol and ergosterol on membrane dynamics: a fluorescence approach.

  title={Influence of cholesterol and ergosterol on membrane dynamics: a fluorescence approach.},
  author={Ajuna Arora and H. Raghuraman and A. Chattopadhyay},
  journal={Biochemical and biophysical research communications},
  volume={318 4},
  • Ajuna Arora, H. Raghuraman, A. Chattopadhyay
  • Published 2004
  • Biology, Medicine
  • Biochemical and biophysical research communications
  • Sterols are essential membrane components of eukaryotic cells and are important for membrane organization and function. [...] Key Method We have monitored the effect of cholesterol and ergosterol on the dynamic properties of both fluid (POPC) and gel (DPPC) phase membranes utilizing the environment-sensitive fluorescent membrane probe DPH. Our results from steady state and time-resolved fluorescence measurements show, for the first time, differential effects of ergosterol and cholesterol toward membrane…Expand Abstract
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