Influence of cetirizine and loratadine on granulocyte-macrophage colony-stimulating factor and interleukin-8 release in A549 human airway epithelial cells stimulated with interleukin-1beta.

@article{Cheng2006InfluenceOC,
  title={Influence of cetirizine and loratadine on granulocyte-macrophage colony-stimulating factor and interleukin-8 release in A549 human airway epithelial cells stimulated with interleukin-1beta.},
  author={Kuo Chu Cheng and Jeng Yuan Hsu and Lin-Shien Fu and Wen Chi Chang and Jao Jia Chu and Chin Shiang Chi},
  journal={Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi},
  year={2006},
  volume={39 3},
  pages={206-11}
}
BACKGROUND AND PURPOSE In addition to being antagonists of histamine receptors, some antihistamines modulate the pathogenesis of allergic inflammation by reducing mediator release, adhesion molecule expression and, consequently, recruitment of inflammatory cells. The aim of this study was to explore the effects of 2 second-generation antihistamines, cetirizine and loratadine, on granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-8 (IL-8) secretions in human airway… CONTINUE READING