Influence of catecholamines on dexamphetamine-induced changes in locomotor activity

@article{Handley1978InfluenceOC,
  title={Influence of catecholamines on dexamphetamine-induced changes in locomotor activity},
  author={Sheila L. Handley and Karin V. Thomas},
  journal={Psychopharmacology},
  year={1978},
  volume={58},
  pages={283-288}
}
  • Sheila L. Handley, Karin V. Thomas
  • Published 1978
  • Psychology, Medicine
  • Psychopharmacology
  • In the mouse, central noradrenaline receptor stimulation by clonidine, or intracerebroventricular injection of noradrenaline or α-methylnoradrenaline, caused marked enhancement of the locomotor stimulant effects of dexamphetamine in doses that were without effect when given alone. A minimally locomotor-stimulant dose of apomorphine reduced the effect of dexamphetamine. Pimozide and phenoxybenzamine each virtually abolished locomotor stimulation after dexamphetamine, while FLA63 caused… CONTINUE READING

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