Influence of caffeine and caffeine withdrawal on headache and cerebral blood flow velocities.

@article{Couturier1997InfluenceOC,
  title={Influence of caffeine and caffeine withdrawal on headache and cerebral blood flow velocities.},
  author={Emile G. M. Couturier and D. Martin Laman and Marijtje van Duijn and Hans van Duijn},
  journal={Cephalalgia : an international journal of headache},
  year={1997},
  volume={17 3},
  pages={
          188-90
        }
}
Caffeine consumption may cause headache, particularly migraine. Its withdrawal also produces headaches and may be related to weekend migraine attacks. Transcranial Doppler sonography (TCD) has shown changes in cerebral blood flow velocities (BFV) during and between attacks of migraine. In order to examine whether headache and changes in BFV could develop from controlled caffeine alterations, 20 healthy volunteers without a headache history, underwent clinical evaluation, TCD and serum caffeine… CONTINUE READING
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